The effective functionalization of CH bond in methane, the main hydrocarbon component in Earth's crust and the most real source of energy for mankind in the nearest observable future, is undoubtedly can be regarded nowadays as one of the most important scientific and technological tasks. However, the usual practice of considering catalytic and gas-phase processes as independent technological branches seriously restricts the possibilities for a deeper understanding and technological optimization of real processes. The development of more effective technologies to convert methane and other gas-phase hydrocarbons into more valuable and demanded chemicals needs a complex approach based on the combined heterogeneous–homogeneous chemistry of these processes. A number of examples are used to illustrate the interconnection between heterogeneous catalytic and gas-phase processes in oxidative functionalization of methane. A number of potential possibilities for the optimization of the real heterogeneous–homogeneous chemistry of these processes are discussed.

C的有效功能化甲烷中的氢键是地壳中的主要碳氢化合物，也是人类在最近可观察到的最真实的能源，无疑如今已被视为最重要的科学技术任务之一。但是，将催化过程和气相过程视为独立的技术分支的通常做法严重限制了对真实过程进行更深入了解和技术优化的可能性。为了将甲烷和其他气相碳氢化合物转化为更有价值和需要的化学物质，要开发更有效的技术，需要基于这些过程的异质-均相化学结合的复杂方法。许多例子用来说明甲烷氧化官能化中非均相催化和气相过程之间的相互联系。讨论了优化这些过程中真正的异质-均质化学的许多潜在可能性。