Recently, photosensitized oxidation has been explored in many fields of research and applications, such as photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT). Although the photosensitized generation of ROS features emerging applications, controllable management of the photosensitization process is still sometimes problematic. DNA has long been considered the carrier for genetic information. With the in-depth study of the chemical properties of DNA, the molecular function of DNA is gradually witnessed by the scientific community. Undoubtedly, the selective recognition nature of DNA endows them excellent candidate modulators for photosensitized oxidation. According to current research, reports on DNA regulation of photosensitized oxidation can be roughly divided into two categories in principle: P-Q quenching pair-switched photosensitization and host-guest interaction-switched photosensitization. In this review, the development status of these two analytical methods will be summarized, and the future development direction of DNA-modulated photosensitization in biosensing and environmental monitoring will also be prospected.

最近，在许多研究和应用领域中已经探索了光敏氧化，例如光动力疗法（PDT）和光动力抗菌化学疗法（PACT）。尽管光敏化的ROS具有新兴的应用功能，但是光敏化过程的可控管理有时仍然是有问题的。DNA长期以来一直被认为是遗传信息的载体。随着对DNA化学性质的深入研究，科学界逐渐见证了DNA的分子功能。毫无疑问，DNA的选择性识别特性使它们成为光敏氧化的优秀候选调节剂。根据目前的研究，有关光敏氧化的DNA调节的报告原则上可以大致分为两类：PQ淬灭对切换光敏化和主客体交互作用切换光敏化。本文综述了这两种分析方法的发展现状，并展望了DNA调节光敏技术在生物传感和环境监测中的未来发展方向。