Objective To assess whether aerobic exercise was superior to usual care in alleviating depressive symptoms in patients living with a major non-communicable disease. Data sources Data were obtained from online databases (PubMed, PsycINFO and SPORTDiscus) as well as from reference lists. The search and collection of eligible studies was conducted up to 18 October 2018 (PROSPERO registration number CRD42017069089). Study selection We included interventions that compared aerobic exercise with usual care in adults who reported depressive symptoms (ie, not necessarily the clinical diagnosis of depression) and were living with a major non-communicable disease. Results Twenty-four studies were included in the meta-analysis (4111 patients). Aerobic exercise alleviated depressive symptoms better than did usual care (standardised mean difference (SMD)=0.50; 95% CI 0.25 to 0.76; Grading of Recommendations Assessment, Development and Evaluation: low quality). Aerobic exercise was particularly effective in alleviating depressive symptoms in cardiac patients (SMD=0.67; 95% CI 0.35 to 0.99). Conclusion Aerobic exercise alleviated depressive symptoms in patients living with a major non-communicable disease, particularly in cardiac populations. Whether aerobic exercise treats clinically diagnosed depression was outside the scope of this study.

中文翻译：

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有氧运动减轻主要非传染性慢性病患者的抑郁症状：系统评价和荟萃分析

目的 评估有氧运动在缓解重大非传染性疾病患者的抑郁症状方面是否优于常规护理。数据来源 数据来自在线数据库（PubMed、PsycINFO 和 SPORTDiscus）以及参考列表。检索和收集符合条件的研究截至 2018 年 10 月 18 日（PROSPERO 注册号 CRD42017069089）。研究选择 我们纳入了对报告有抑郁症状（即不一定是抑郁症的临床诊断）且患有严重非传染性疾病的成年人进行有氧运动与常规护理进行比较的干预措施。结果 荟萃分析纳入了 24 项研究（4111 名患者）。有氧运动比常规护理更能缓解抑郁症状（标准化平均差（SMD）=0.50；95% CI 0.25 至 0.76；建议分级评估、制定和评价：低质量）。有氧运动对缓解心脏病患者的抑郁症状特别有效（SMD=0.67；95% CI 0.35 至 0.99）。结论 有氧运动减轻了患有严重非传染性疾病的患者的抑郁症状，特别是在心脏病患者中。有氧运动是否治疗临床诊断的抑郁症不在本研究的范围内。特别是在心脏病人群中。有氧运动是否治疗临床诊断的抑郁症不在本研究的范围内。特别是在心脏病人群中。有氧运动是否治疗临床诊断的抑郁症不在本研究的范围内。