Cytorhizins A–D, four novel polyketide heterodimers, were isolated from the endophytic fungus Cytospora rhizophorae A761. These new compounds shared an unprecedented 6/6/5/6/8 or 6/6/5/6/7 pentacyclic ring system and fused as a fascinating cagelike skeleton, embodying by a polyoxygenated isopentyl unit and a highly structure-combined benzophenone scaffold. Their structures were elucidated by extensive spectroscopic analyses and X-ray diffraction techniques. Moreover, compounds 1–4 were evaluated for in vitro cytotoxicity and antimicrobial activity.

中文翻译：

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Cytorhizins A–D，来自内生真菌Cytospora rhizophorae的四个高度结构结合的二苯甲酮

Cytohizins A–D是四种新型的聚酮化合物异二聚体，是从内生真菌Cytospora rhizophorae A761中分离得到的。这些新化合物共享空前的6/6/5/6/8或6/6/5/6/7五环系统，并融合成迷人的笼状骨架，由聚氧异戊基单元和高度结构结合的二苯甲酮骨架组成。通过广泛的光谱分析和X射线衍射技术阐明了它们的结构。此外，化合物1 - 4被用于体外细胞毒性和抗微生物活性进行评价。