We present a total synthesis of the fungal natural product graphislactone G, a chlorinated resorcylic lactone. The key step is a Suzuki coupling used for the construction of the central biaryl bond. Graphislactone G was prepared in 13 steps with 22% yield starting with orcinol and phloroglucinic acid, where the longest linear sequence consists of nine steps.

中文翻译：

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石墨烯内酯G的全合成

我们提出了真菌天然产物石墨内酯G（一种氯化间苯二酸内酯）的全合成。关键步骤是用于构建中央联芳基键的Suzuki偶联。Graphislactone G的制备是由13步制备的，从二十二烷酸和间苯二甲酸开始，产率为22％，其中最长的线性序列由9步组成。