Gold nanoparticles (AuNPs) have arisen a lot of interest in the clinical realms of nanomedicine. Despite the large advances made in cancer research using AuNPs, their use in tissue engineering and regenerative medicine (TERM) is still in its infancy. Herein, it is discussed the properties, functionalization, and emerging use of AuNPs as a multifunctional and multimodal platform for drug delivery, phototherapy, diagnostic and cell imaging purposes. Moreover, the recent reports related to the ability of AuNPs to enhance stem cell differentiation for bone tissue engineering, to enhance the mechanical and adhesive properties of scaffolds and surface topography to guide cell behaviors are addressed.

金纳米颗粒（AuNPs）在纳米医学的临床领域引起了很多兴趣。尽管使用AuNPs在癌症研究中取得了巨大进展，但它们在组织工程和再生医学（TERM）中的应用仍处于起步阶段。在本文中，讨论了AuNPs的性质，功能化以及作为药物递送，光疗，诊断和细胞成像目的的多功能和多峰平台的新兴用途。而且，最近的报告涉及AuNP增强骨组织工程干细胞分化，增强支架的机械和粘附特性以及指导细胞行为的表面形貌的能力。