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Fluorescent Properties of the Amidinophenylporphyrins Interacting with DNA
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2012-02-29 , DOI: 10.1002/cjoc.201100564
Kai Wang , Tian Li , Faquan Yu , Yunman Zheng , Wai‐Kwok Wong , Daniel W. J. Kwong , Zaoying Li

5,10,15,20‐Tetrakis(4‐amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.

中文翻译:

与DNA相互作用的por基苯基卟啉的荧光性质

通过荧光发射光谱研究了5,10,15,20-四(4-ami啶醇苯基)卟啉,其锌配合物和a基苯基双卟啉与小牛胸腺DNA的相互作用,并显示了荧光寿命。记录这些化合物的结合模式,并测量发光寿命作为自然函数,以了解与DNA的相互作用。结果表明,那些氨基卟啉是有前途的新型光动力治疗剂。
更新日期:2012-02-29
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