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Herbicide discovery in light of rapidly spreading resistance and ever‐increasing regulatory hurdles
Pest Management Science ( IF 4.1 ) Pub Date : 2017-12-06 , DOI: 10.1002/ps.4768
Bodo Peters 1 , Harry J Strek 1
Affiliation  

According to the United Nations, the global population is expected to grow to almost 10 billion people in 2050. This means that the demand for food, feed and fiber will double while at the same time, agriculture is being challenged by a scarcity of water, global warming, less land available for farming, protection of natural habitats, a demand for biodiversity on farms and other factors. In addition, crop protection products are under pressure from rapidly spreading resistance and increasing regulatory requirements. Many regulatory bodies are also moving away from a risk assessment approach to a more hazard‐based approach to grant registrations. Nevertheless, chemical crop protection compounds remain attractive and necessary to combat pests, particularly weeds. Industry has increased its efforts to find new molecules that are highly biologically effective on target species, including resistant populations, but safe for non‐target organisms. To manage resistance in the future, a diverse toolbox is needed that includes herbicides with a variety of different chemistries and modes of action, combined with non‐chemical measures in integrated systems. However, discovering a herbicide and getting it registered and to the market is an extremely complex endeavor full of risk, much of it incalculable. © 2017 Society of Chemical Industry

中文翻译:

鉴于抗药性迅速传播和监管障碍不断增加,发现了除草剂

根据联合国的数据,到2050年,全球人口预计将增长到近100亿。这意味着对食物,饲料和纤维的需求将增加一倍,与此同时,农业正面临着水资源短缺的挑战,全球变暖,可供耕种的土地减少,自然栖息地的保护,农场对生物多样性的需求等因素。另外,农作物保护产品承受着迅速传播的抗药性和日益增加的法规要求的压力。许多监管机构也正在从风险评估方法转变为基于危害的方法来进行注册。尽管如此,化学作物保护化合物仍然具有吸引力,并且对防治害虫(尤其是杂草)是必不可少的。工业界已加大努力,寻找对目标物种(包括抗性种群)具有高生物学活性但对非目标生物安全的新分子。为了在将来管理耐药性,需要一个多样化的工具箱,其中包括具有各种不同化学性质和作用方式的除草剂,以及集成系统中的非化学措施。然而,发现除草剂并进行注册并推向市场是一项充满风险的极其复杂的工作,其中很多是无法估量的。©2017化学工业协会 结合集成系统中的非化学措施。然而,发现除草剂并进行注册并推向市场是一项充满风险的极其复杂的工作,其中很多是无法估量的。©2017化学工业协会 结合集成系统中的非化学措施。然而,发现除草剂并进行注册并推向市场是一项充满风险的极其复杂的工作,其中很多是无法估量的。©2017化学工业协会
更新日期:2017-12-06
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