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Tranexamic acid for post-partum haemorrhage in the WOMAN trial
The Lancet ( IF 98.4 ) Pub Date : 2017-09-30 , DOI: 10.1016/s0140-6736(17)31956-6
Kim Hinshaw

As one of the many collaborators who contributed to the WOMAN trial1 our team's involvement in research that will improve maternal outcomes globally has been gratifying. 1 g of intravenous tranexamic acid given within 3 h of post-partum haemorrhage significantly reduced maternal death and the need for surgery (laparotomy). The fact that post-partum haemorrhage was defined as 500 mL or more for vaginal deliveries but 1000 mL or more for caesarean section is important to note. This difference should be considered when clinicians update local guidelines for post-partum haemorrhage.

中文翻译:

在妇女试验中使用氨甲环酸治疗产后出血

作为为WOMAN试验1做出贡献的众多合作者之一,我们的团队参与了旨在改善全球孕产妇结局的研究,这一结果令人欣喜。产后出血后3小时内给予1 g静脉给予氨甲环酸,可显着减少产妇死亡和手术需求(开腹手术)。重要的是要注意以下事实:阴道分娩的产后出血定义为500 mL或更高,而剖腹产的定义为1000 mL或更高。当临床医生更新产后出血的当地指南时,应考虑这种差异。
更新日期:2017-09-29
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