The qualitative and quantitative identification of low mass isotopes in the mass range 1–6 u poses certain difficulties when attempting to achieve the required resolution with an instrument suitable for deployment within a process environment. Certain adjacent species present in the process sample (HT and D₂) require a resolution greater than 930 to achieve an accurate measurement. We demonstrate here through simulation techniques that this level of performance required is unachievable using commercially available instruments. Using previously reported simulation techniques, this article demonstrates how the required performance for resolving the low mass isotopes can be achieved by a quadrupole mass spectrometer (QMS), which incorporates a quadrupole mass filter (QMF) constructed from hyperbolic electrodes and operated in zone 3 of the Mathieu stability diagram.

质量范围为 1-6 u 的低质量同位素的定性和定量鉴定在尝试使用适合在过程环境中部署的仪器达到所需的分辨率时带来了一定的困难。工艺样品中存在的某些相邻物种（HT 和 D ₂) 需要大于 930 的分辨率才能实现准确的测量。我们在此通过仿真技术证明，使用市售仪器无法达到所需的这种性能水平。本文使用先前报道的模拟技术，展示了如何通过四极杆质谱仪 (QMS) 实现解析低质量同位素所需的性能，该质谱仪结合了由双曲面电极构建并在区域 3 中运行的四极杆质量过滤器 (QMF)。 Mathieu 稳定性图。