FT-ICR mass spectrometry, together with collision-induced dissociation and electron capture dissociation, has been used to characterize the polyphosphoester poly[1,4-bis(hydroxyethyl)terephthalate-alt-ethyloxyphosphate] and its degradation products. Three degradation pathways were elucidated: hydrolysis of the phosphate-[1,4-bis(hydroxyethyl)terephthalate] bonds; hydrolysis of the phosphate-ethoxy bonds; and hydrolysis of the ethyl-terephthalate bonds. The dominant degradation reactions were those that involved the phosphate groups. This work constitutes the first application of mass spectrometry to the characterization of polyphosphoesters and demonstrates the suitability of high mass accuracy FT-ICR mass spectrometry, with CID and ECD, for the structural analysis of polyphosphoesters and their degradation products.

FT-ICR质谱法，与碰撞诱导解离和电子捕获解离一起，已被用于表征聚磷酸酯聚[1,4-双（羟乙基）对苯二甲酸酯中高音-乙氧基磷酸酯]及其降解产物。阐明了三种降解途径：磷酸酯-[1,4-双（羟乙基）对苯二甲酸酯]键的水解；磷酸-乙氧基键的水解；和对苯二甲酸乙酯键的水解。主要的降解反应是那些涉及磷酸基团的反应。这项工作构成了质谱在聚磷酸酯表征中的首次应用，并证明了具有 CID 和 ECD 的高质量准确度 FT-ICR 质谱法适用于聚磷酸酯及其降解产物的结构分析。