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Label-free optical resonant sensors for biochemical applications
Progress in Quantum Electronics ( IF 7.4 ) Pub Date : 2013-03-01 , DOI: 10.1016/j.pquantelec.2013.02.001
Caterina Ciminelli , Clarissa Martina Campanella , Francesco Dell’Olio , Carlo Edoardo Campanella , Mario Nicola Armenise

Abstract For a number of years, the scientific community has been paying growing attention to the monitoring and enhancement of public health and the quality of life through the detection of all dangerous agents for the human body, including gases, proteins, virus, and bacterial agents. When these agents are detected through label-free biochemical sensors, the molecules are not modified structurally or functionally by adding fluorescent or radioactive dyes. This work focuses on label-free optical ring resonator-based configurations suited for bio-chemical sensing, highlighting their physical aspects and specific applications. Resonant wavelength shift and the modal splitting occurring when the analyte interacts with microresonant structures are the two major physical aspects analyzed in this paper. Competitive optical platforms proposed in the literature are also illustrated together with their properties and performance.

中文翻译:

用于生化应用的无标签光学谐振传感器

摘要 多年来,科学界越来越关注通过检测所有对人体有害的物质,包括气体、蛋白质、病毒和细菌剂,来监测和提高公众健康和生活质量。 . 当通过无标记生化传感器检测这些试剂时,不会通过添加荧光或放射性染料来改变分子的结构或功能。这项工作侧重于适用于生物化学传感的基于无标记光学环形谐振器的配置,重点介绍了它们的物理方面和特定应用。分析物与微谐振结构相互作用时发生的谐振波长偏移和模态分裂是本文分析的两个主要物理方面。
更新日期:2013-03-01
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