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Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles.
Journal of Chromatographic Science ( IF 1.5 ) Pub Date : 2006 Feb
Billiot, Fereshteh H, Billiot, Eugene J, Ng, Yuen Kwun, Warner, Isiah M

In this study, 18 polymeric single amino acid and dipeptide surfactants are examined, and their performances, in terms of enantioselectivity, are compared for norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, benzoin, benzoin methyl, and benzoin ethyl enantiomers. Several aspects of amino acid-based polymeric surfactants including comparison of single amino acid versus dipeptide, amino acid order, steric effect, and effect of the position of the chiral center of dipeptide surfactants on the chiral selectivity of these optically active compounds are discussed.

中文翻译:

使用基于氨基酸的分子胶束,手性分离去甲月桂碱,月桂碱,月桂碱,氯噻酮和三种安息香衍生物。

在这项研究中,检查了18种聚合的单氨基酸和二肽表面活性剂,并比较了其在对映选择性方面的性能,如去甲月桂果碱,月桂酸,月桂丹碱,氯噻酮,苯偶姻,苯偶姻甲基和苯偶姻乙基对映异构体。讨论了基于氨基酸的聚合物表面活性剂的几个方面,包括单个氨基酸与二肽的比较,氨基酸顺序,空间效应以及二肽表面活性剂的手性中心位置对这些旋光化合物的手性选择性的影响。
更新日期:2017-01-31
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