The first direct catalytic asymmetric alpha-amination of aldehydes is described herein. alpha-Unbranched aldehydes react in this novel proline-catalyzed reaction with dialkyl azodicarboxylates to give alpha-amino aldehydes in excellent yields and enantioselectivities.

中文翻译：

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醛的直接催化不对称α-胺化。

本文描述了醛的第一次直接催化不对称α-胺化。在这种新的脯氨酸催化的反应中，α-直链醛与偶氮二羧酸二烷基酯反应生成α-氨基醛，收率和对映选择性极好。