The widespread use of nanodiamond as a biomedical platform for drug-delivery, imaging, and subcellular tracking applications stems from its nontoxicity and unique quantum mechanical properties. Here, we extend this functionality to the domain of magnetic resonance, by demonstrating that the intrinsic electron spins on the nanodiamond surface can be used to hyperpolarize adsorbed liquid compounds at low fields and room temperature. By combining relaxation measurements with hyperpolarization, spins on the surface of the nanodiamond can be distinguished from those in the bulk liquid. These results are likely of use in signaling the controlled release of pharmaceutical payloads.

中文翻译：

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超极化纳米金刚石表面

纳米金刚石作为药物输送、成像和亚细胞追踪应用的生物医学平台的广泛使用源于其无毒和独特的量子力学性能。在这里，我们通过证明纳米金刚石表面的本征电子自旋可用于在低场和室温下超极化吸附的液体化合物，将此功能扩展到磁共振领域。通过将弛豫测量与超极化相结合，可以将纳米金刚石表面的自旋与本体液体中的自旋区分开来。这些结果可能用于发出药物有效载荷受控释放的信号。