Chemical investigation of the aerial parts of Atraphaxis frutescens resulted in the isolation of five 7-methoxyflavonols with pyrogallol B-ring moieties (1–5), a fisetinidol glucoside (13), and a benzyl glycoside (18), together with 26 known compounds including flavonoids, phenylpropanoid amides, anthraquinone glycosides, lignans, and a benzyl derivative. The principal chemical structural feature of the isolated compounds was either a pyrogallol or catechol B-ring moiety, and they showed potent 1,1-diphenyl-2-picrylhydrazyl radical scavenging activities. To assess the effects of these antioxidants on biological enzymes, their inhibitory effects against an insect phenoloxidase and a mushroom tyrosinase were evaluated. This study indicated that insect phenoloxidase was inhibited by phenylpropanoid amides and that mushroom tyrosinase was inhibited by the characteristic 7-methoxyflavonol 3-O-rhamnopyranosides.

中文翻译：

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抗氧化剂黄酮类和多酚类化合物从木蓼属紫苏及其对昆虫酚氧化酶和蘑菇酪氨酸酶抑制活性

的地上部分的化学调查木蓼属紫苏导致的五个7 methoxyflavonols与连苯三酚B-环部分（隔离1 - 5），一个非瑟酮葡糖苷（13），和苄糖苷（18），以及26种已知化合物，包括类黄酮，苯基丙烷类酰胺，蒽醌糖苷，木脂素和苄基衍生物。分离出的化合物的主要化学结构特征是邻苯三酚或邻苯二酚B环部分，它们显示出有效的1,1-二苯基-2-吡啶并肼基自由基清除活性。为了评估这些抗氧化剂对生物酶的作用，评估了它们对昆虫酚氧化酶和蘑菇酪氨酸酶的抑制作用。这项研究表明，昆虫苯酚氧化酶被苯基丙烷类酰胺所抑制，而蘑菇酪氨酸酶被特征性的7-甲氧基黄酮醇3- O-鼠李糖吡喃糖苷所抑制。