We present a facile strategy to achieve color-tunability room-temperature phosphorescence (RTP) nanoprobes by doping mineral acids (i.e., boric acid and phosphoric acid) in an organic silicon scaffold through a cross-linking process. Such RTP nanoprobes exhibit inherent tunable phosphorescence (from 420–650 nm) with long lifetime (emission lasting for ∼5–15 s, RTP lifetime: ∼0.53–2.11 s) and high quantum yields (∼13.1–43.0%). Therefore, the as-prepared nanoprobes enable multiple imaging in live cells with a high signal-to-background ratio value of ∼52.

中文翻译：

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用于时间分辨生物成像的矿物酸触发多色室温磷光纳米探针


我们提出了一种简单的策略，通过交联过程在有机硅支架中掺杂无机酸（即硼酸和磷酸）来实现颜色可调的室温磷光（RTP）纳米探针。这种RTP纳米探针表现出固有的可调谐磷光（420-650 nm），具有长寿命（发射持续~5-15 s，RTP寿命：~0.53-2.11 s）和高量子产率（~13.1-43.0%）。因此，所制备的纳米探针能够在活细胞中进行多重成像，信号背景比高达~52。