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K-means clustering of hyperpolarised 13C-MRI identifies intratumoural perfusion/metabolism mismatch in renal cell carcinoma as best predictor of highest grade
medRxiv - Radiology and Imaging Pub Date : 2024-05-08 , DOI: 10.1101/2024.05.06.24306829 Ines Horvat-Menih , Alixander S Khan , Mary A McLean , Joao A G Duarte , Eva Serrao , Stephan Ursprung , Joshua Kaggie , Andrew B Gill , Andrew N Priest , Mireia Crispin-Ortuzar , Anne Y Warren , Sarah J Welsh , Thomas J Mitchell , Grant D Stewart , Ferdia A Gallagher
medRxiv - Radiology and Imaging Pub Date : 2024-05-08 , DOI: 10.1101/2024.05.06.24306829 Ines Horvat-Menih , Alixander S Khan , Mary A McLean , Joao A G Duarte , Eva Serrao , Stephan Ursprung , Joshua Kaggie , Andrew B Gill , Andrew N Priest , Mireia Crispin-Ortuzar , Anne Y Warren , Sarah J Welsh , Thomas J Mitchell , Grant D Stewart , Ferdia A Gallagher
Purpose Conventional renal mass biopsy approaches are inaccurate, potentially leading to undergrading. This study explored using hyperpolarised [1-13C]pyruvate MRI (HP 13C-MRI) to identify the most aggressive areas within the tumour of patients with clear cell renal cell carcinoma (ccRCC).
中文翻译：
超极化 13C-MRI 的 K 均值聚类将肾细胞癌的瘤内灌注/代谢不匹配确定为最高级别的最佳预测因子
目的传统的肾脏肿块活检方法不准确，可能导致降级。本研究探索使用超极化 [1- 13 C]丙酮酸 MRI (HP 13 C-MRI) 来识别透明细胞肾细胞癌 (ccRCC) 患者肿瘤内最具侵袭性的区域。
更新日期：2024-05-11
中文翻译：
超极化 13C-MRI 的 K 均值聚类将肾细胞癌的瘤内灌注/代谢不匹配确定为最高级别的最佳预测因子
目的传统的肾脏肿块活检方法不准确，可能导致降级。本研究探索使用超极化 [1- 13 C]丙酮酸 MRI (HP 13 C-MRI) 来识别透明细胞肾细胞癌 (ccRCC) 患者肿瘤内最具侵袭性的区域。
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