An efficient, mild, and regioselective synthesis of substituted 1‐methyl‐1H‐tetrazole using methyl 2,2,2‐trichloroacetimidate is described. The substrate scope of the methodology has been established with wide variety of tetrazoles. N1‐Methylated tetrazoles were synthesized with high yields (85%–97%).

中文翻译：

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1H-四唑与 2,2,2-三氯乙酰亚氨酸甲酯的区域选择性 N1-甲基化


描述了使用 2,2,2-三氯乙酰亚氨酸甲酯高效、温和且区域选择性合成取代的 1-甲基-1H-四唑。该方法的底物范围已确定为多种四唑。 N1-甲基化四唑的合成收率很高（85%–97%）。