Deep eutectic solvents (DES) emerge as promising alternatives to conventional solvents, offering outstanding extraction capabilities, low toxicity, eco-friendliness, straightforward synthesis procedures, broad applicability, and impressive recyclability. DES are synthesized by combining two or more components through various synthesis procedures, such as heat-assisted mixing/stirring, grinding, freeze drying, and evaporation. Polysaccharides, as abundant natural materials, are highly valued for their biocompatibility, biodegradability, and sustainability. These versatile biopolymers can be derived from various natural sources such as plants, algae, animals, or microorganisms using diverse extraction techniques. This review explores the synthesis procedures of DES, their physicochemical properties, characterization analysis, and their application in polysaccharide extraction. The extraction optimization strategies, parameters affecting DES-based polysaccharide extraction, and separation mechanisms are comprehensively discussed. Additionally, this review provides insights into recently developed molecular guides for DES screening and the utilization of artificial neural networks for optimizing DES-based extraction processes. DES serve as excellent extraction media for polysaccharides from different sources, preserving their functional features. They are utilized both as extraction solvents and as supporting media to enhance the extraction abilities of other solvents. Continued research aims to improve DES-based extraction methods and achieve selective, energy-efficient processes to meet the demands of this expanding field.

中文翻译：

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低共熔溶剂作为可持续提取介质从天然来源中提取多糖：现状、挑战和前景


低共熔溶剂 (DES) 成为传统溶剂的有前途的替代品，具有出色的萃取能力、低毒性、生态友好性、简单的合成程序、广泛的适用性和令人印象深刻的可回收性。 DES 是通过各种合成程序（例如热辅助混合/搅拌、研磨、冷冻干燥和蒸发）将两种或多种组分组合而合成的。多糖作为丰富的天然材料，因其生物相容性、生物可降解性和可持续性而受到高度重视。这些多功能生物聚合物可以使用不同的提取技术从各种天然来源中获得，例如植物、藻类、动物或微生物。本文探讨了 DES 的合成程序、其理化性质、表征分析及其在多糖提取中的应用。全面讨论了提取优化策略、影响 DES 多糖提取的参数以及分离机制。此外，本综述还深入介绍了最近开发的 DES 筛选分子指南以及利用人工神经网络来优化基于 DES 的提取过程。 DES 是不同来源多糖的优异提取介质，保留了其功能特性。它们既可用作萃取溶剂，也可用作支持介质，以增强其他溶剂的萃取能力。持续的研究旨在改进基于 DES 的提取方法，并实现选择性、节能的工艺，以满足这一不断扩大的领域的需求。