Surface Enhanced Raman Scattering (SERS) technology is a fast and highly sensitive optical detection technique for trace detection in food testing and has been developing rapidly. Meanwhile, the application of dual-mode detection technology in food safety is also maturing, where the combination of two sensing modes not only compensates for the shortcomings of a single sensing mode, but also significantly reduces the possibility of false positives and has a lower detection limit. Therefore, it is important to combine SERS with other detection techniques for rapid, accurate and portable detection in food safety. This paper describes the progress in the construction of SERS-based dual-mode biosensing technology in recent years and discusses the prospect of its application in the field of food safety. Firstly, it introduces the classification and working principle of SERS-based dual-mode sensing; then it systematically summarizes the latest progress of the application of SERS-based dual-mode sensing detection technology, such as the detection of pathogenic bacteria, biotoxins, drug residues, etc. Also, some of the material choices for constructing SERS dual-mode sensors are summarized. In addition, future opportunities and challenges are presented. Emerging SERS-based dual-mode detection technologies show great potential for monitoring harmful substances in food. A part of SERS dual-mode sensor is very promising for rapid detection of food contaminants in the field. At the same time, some emerging materials can be used for SERS substrates. In addition, some technologies can provide a better platform for partial SERS dual-mode sensors to achieve food detection.

中文翻译：

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基于SERS的双模式传感技术策略研究进展及其在食品中有害物质检测中的应用

表面增强拉曼散射（SERS）技术是一种快速、高灵敏度的光学检测技术，用于食品检测中的痕量检测，并得到迅速发展。同时，双模式检测技术在食品安全中的应用也日趋成熟，两种传感模式的结合不仅弥补了单一传感模式的缺点，而且显着降低了误报的可能性，检测率较低。限制。因此，将SERS与其他检测技术相结合，对食品安全进行快速、准确、便携式检测具有重要意义。本文介绍了近年来基于SERS的双模生物传感技术的构建进展，并探讨了其在食品安全领域的应用前景。首先介绍了基于SERS的双模传感的分类和工作原理；然后系统总结了基于SERS的双模传感检测技术应用的最新进展，如病原菌、生物毒素、药物残留等的检测，以及构建SERS双模传感器的一些材料选择进行了总结。此外，还提出了未来的机遇和挑战。新兴的基于SERS的双模式检测技术在监测食品中的有害物质方面显示出巨大的潜力。 SERS双模式传感器的一部分对于现场食品污染物的快速检测非常有前景。同时，一些新兴材料可用于SERS基底。此外，一些技术可以为部分SERS双模传感器实现食品检测提供更好的平台。