Herein the substrate scope of a nickel-catalysed syn-selective arylnickelation and cyclisation with arylboronic acids is expanded to include ketone and imine-tethered terminal alkynes. The reaction proceeds via a syn-aryl nickelation of a terminal alkyne followed by cyclisation of the resulting alkenylnickel species. Along with this the first enantioselective version of the reaction has been developed using PHIM type P,N ligands.

中文翻译：

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镍催化顺式选择性芳基镍化和酮/亚胺连接的末端炔烃与芳基硼酸的环化

本文中，镍催化的顺式选择性芳基镍化和芳基硼酸环化的底物范围扩大到包括酮和亚胺连接的末端炔烃。该反应通过末端炔烃的顺式芳基镍化进行，然后将所得烯基镍物质环化。与此同时，使用 PHIM 型 P,N 配体开发了该反应的第一个对映选择性版本。