This systematic review and -analysis of randomized controlled trials (RCTs) sought to evaluate the effects of quercetin on the components of (MetS) such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). A systematic literature search up to December 2023 was completed in Scopus, PubMed, Embase, and Web of Science, to identify eligible RCTs. Altogether, 20 studies with a total sample size of 1,164 subjects were included in the analysis. A pooled analysis showed that quercetin consumption led to a significant reduction in FBG (WMD: −1.03 mg/dL; 95 % CI: −1.87 to −0.19), and SBP (WMD: −1.96 mmHg; 95 % CI: −3.11 to −0.81). However, there were no significant effects on TG, HDL-C, WC, and DBP. It was found that quercetin intake can decrease FBG and SBP significantly without significant effects on other components of MetS.

中文翻译：

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补充槲皮素对成人代谢综合征各组成部分的影响：随机对照试验的系统评价和剂量反应荟萃分析


这项随机对照试验 (RCT) 的系统回顾和分析旨在评估槲皮素对 (MetS) 组成部分的影响，例如腰围 (WC)、收缩压 (SBP)、舒张压 (DBP)、空腹血压血糖（FBG）、甘油三酯（TG）和高密度脂蛋白胆固醇（HDL-C）。在 Scopus、PubMed、Embase 和 Web of Science 中完成了截至 2023 年 12 月的系统文献检索，以确定符合条件的 RCT。分析中总共纳入了 20 项研究，总样本量为 1,164 名受试者。汇总分析显示，槲皮素消耗导致 FBG（WMD：-1.03 mg/dL；95% CI：-1.87 至 -0.19）和 SBP（WMD：-1.96 mmHg；95% CI：-3.11 至 -0.19）显着降低。 −0.81）。然而，对 TG、HDL-C、WC 和 DBP 没有显着影响。研究发现，摄入槲皮素可以显着降低 FBG 和 SBP，而对 MetS 的其他成分没有显着影响。