Sulforaphane (SFN) has anti-inflammatory properties, and is found in broccoli sprouts. Studies suggest that it protects against disease due to its anti-inflammatory activity. The impact of SFN on healthy people undergoing a surgical procedure has not been investigated. To explore the effect of SFN in living kidney donors on the postoperative inflammatory response and recovery. We performed a double-blind randomised controlled trial where donors followed a SFN-enriched (8 mg) preoperative diet. A total of 42 donors were included, there were no significant differences at baseline. Postoperative inflammatory response was consistent among both arms and subjective recovery showed no significant difference. Findings regarding postoperative kidney function suggest no consistently significant impact. A well-defined SFN-enriched diet did not have anti-inflammatory or a clinically relevant effect on the outcome. Due to the complexity of dietary modification of the inflammatory response, additional research is needed.

中文翻译：

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术前饮食摄入低剂量萝卜硫素对活体肾移植没有临床显着影响


萝卜硫素 (SFN) 具有抗炎特性，存在于西兰花芽中。研究表明，它具有抗炎活性，可以预防疾病。 SFN 对接受外科手术的健康人的影响尚未得到研究。探讨活体肾捐献者SFN对术后炎症反应及恢复的影响。我们进行了一项双盲随机对照试验，捐赠者术前遵循富含 SFN（8 毫克）的饮食。总共包括 42 名捐赠者，基线时没有显着差异。两组术后炎症反应一致，主观恢复情况无显着差异。关于术后肾功能的研究结果表明没有持续显着的影响。明确的富含 SFN 的饮食不会对结果产生抗炎或临床相关影响。由于炎症反应的饮食调节非常复杂，因此需要进行更多研究。