Purpose

To evaluate the quality of life, sexual function, anxiety, and depression of women with endometriosis according to pain symptoms and infertility.

Methods

This cross-sectional multicenter study included 229 women with endometriosis followed up at a tertiary hospital in Campinas, a tertiary hospital in São Paulo, and a reproductive medicine clinic in Campinas from 2018 to 2021. The women were divided into four groups according to the presence of pain symptoms and infertility. The Endometriosis Health Profile Questionnaire, Female Sexual Function Index, Beck Depression Inventory, and Beck Anxiety Index were applied to assess quality of life, sexual function, depression, and anxiety of women with endometriosis.

Results

The women were grouped as follows: group 1 (45 women without infertility and without pain), group 2 (73 women without infertility and with pain), group 3 (49 women with infertility and without pain), and group 4 (62 women with infertility and pain). Of the women with infertility, the majority had primary infertility. Most women had deep endometriosis (p = 0.608). Women with pain had higher anxiety and depression scores and worse quality of life than women without pain (p < 0.001). Regarding sexual function, all the groups were at risk for sexual dysfunction (p = 0.671). The group of women with pain and infertility have worse anxiety scores (25.31 ± 15.96) and depression (18.81 ± 11.16) than the other groups.

Conclusion

Pain symptoms worsen anxiety, depression, and quality of life of women with endometriosis and when associated with infertility, greater impairment of psychological aspects may occur.

中文翻译：

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根据疼痛和不孕评估子宫内膜异位症女性的生活质量、心理方面和性功能：一项横断面研究

目的

根据疼痛症状和不孕情况评估子宫内膜异位症女性的生活质量、性功能、焦虑和抑郁情况。

方法

这项横断面多中心研究纳入了 229 名患有子宫内膜异位症的女性，她们于 2018 年至 2021 年间在坎皮纳斯的一家三级医院、圣保罗的一家三级医院以及坎皮纳斯的一家生殖医学诊所进行了随访。根据是否存在子宫内膜异位症，这些女性被分为四组疼痛症状和不孕症。采用子宫内膜异位症健康状况调查表、女性性功能指数、贝克抑郁量表和贝克焦虑指数来评估子宫内膜异位症女性的生活质量、性功能、抑郁和焦虑。

结果

这些妇女被分组如下：第 1 组（45 名无不孕且无疼痛的妇女）、第 2 组（73 名无不孕且无疼痛的妇女）、第 3 组（49 名不孕且无疼痛的妇女）和第 4 组（62 名无不孕且无疼痛的妇女）。不孕和疼痛）。在不孕症女性中，大多数为原发性不孕症。大多数女性患有深部子宫内膜异位症（p  = 0.608）。与没有疼痛的女性相比，患有疼痛的女性焦虑和抑郁评分更高，生活质量更差 ( p  < 0.001)。关于性功能，所有组都面临性功能障碍的风险（p  = 0.671）。患有疼痛和不孕症的女性组的焦虑评分（25.31±15.96）和抑郁评分（18.81±11.16）比其他组更差。

结论

疼痛症状会加剧子宫内膜异位症女性的焦虑、抑郁和生活质量，并且当与不孕相关时，可能会出现更大的心理损害。