Higher levels of physical activity are known to benefit aspects of brain health across the lifespan. However, the role of sedentary behavior (SB) is less well understood. In this review we summarize and discuss evidence on the role of SB on brain health (including cognitive performance, structural or functional brain measures, and dementia risk) for different age groups, critically compare assessment approaches to capture SB, and offer insights into emerging opportunities to assess SB via digital technologies. Across the lifespan, specific characteristics of SB (particularly whether they are cognitively active or cognitively passive) potentially act as moderators influencing the associations between SB and specific brain health outcomes. We outline challenges and opportunities for future research aiming to provide more robust empirical evidence on these observations.

中文翻译：

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久坐行为和寿命大脑健康

众所周知，较高水平的体力活动有益于一生中大脑健康的各个方面。然而，人们对久坐行为 (SB) 的作用还不太了解。在这篇综述中，我们总结并讨论了 SB 对不同年龄组的大脑健康（包括认知表现、结构或功能性大脑测量以及痴呆风险）的作用的证据，批判性地比较了捕获 SB 的评估方法，并提供了对新兴机会的见解通过数字技术评估SB。在整个生命周期中，SB 的特定特征（特别是认知主动型​​还是认知被动型）可能充当影响 SB 与特定大脑健康结果之间关联的调节因素。我们概述了未来研究的挑战和机遇，旨在为这些观察结果提供更强有力的经验证据。