An oxidative strategy for the preparation of dihydrobenzofurans via heterogeneous photocatalysis is reported. This method leverages the surface interaction between the alkenyl phenol and the TiO₂ solid surface, which enables direct activation by visible light without the need for pre-functionalization or surface modification. The resulting alkenyl phenoxyl radical is proposed to be selectively captured by a neutral phenol nucleophile, rendering β-5′ coupling with excellent chemo- and regio-selectivity. The reaction proceeds under benign conditions, using an inexpensive, nontoxic, and recyclable photocatalyst under visible light irradiation with air as the terminal oxidant at room temperature.

中文翻译：

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可见光 TiO2 催化酚与烯基酚氧化[3+2]成环合成二氢苯并呋喃

报道了通过非均相光催化制备二氢苯并呋喃的氧化策略。该方法利用烯基苯酚和TiO ₂固体表面之间的表面相互作用，从而能够通过可见光直接激活，而不需要预功能化或表面改性。由此产生的烯基苯氧基自由基被中性苯酚亲核试剂选择性捕获，使 β-5' 偶联具有优异的化学和区域选择性。该反应在良性条件下进行，使用廉价、无毒且可回收的光催化剂，在可见光照射下，以空气作为终端氧化剂，在室温下进行。