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Targeting the PIEZO1 pathway boosts T cell antitumour cytotoxicity
Nature Biomedical Engineering ( IF 28.1 ) Pub Date : 2024-03-27 , DOI: 10.1038/s41551-024-01189-4


The mechanical sensor PIEZO1 regulates the traction force that is critical for cytotoxic T cells to target tumour cells. This finding creates avenues for enhancing the efficacy of T cell-targeted immune therapies.

中文翻译:

靶向 PIEZO1 通路增强 T 细胞抗肿瘤细胞毒性

机械传感器 PIEZO1 调节牵引力,这对于细胞毒性 T 细胞靶向肿瘤细胞至关重要。这一发现为增强 T 细胞靶向免疫疗法的功效创造了途径。
更新日期:2024-03-27
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