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RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties
mAbs ( IF 5.3 ) Pub Date : 2024-03-25 , DOI: 10.1080/19420862.2024.2330113
Barnabas Nyesiga 1, 2 , Mattias Levin 1 , Anna Säll 1 , Anna Rosén 1 , Kim Jansson 1 , Sara Fritzell 1 , Karin Hägerbrand 1 , Dietmar Weilguny 1 , Laura von Schantz 1
Affiliation  

Despite the large number of existing bispecific antibody (bsAb) formats, the generation of novel bsAbs is still associated with development and bioprocessing challenges. Here, we present RUBY, a no...

中文翻译:

RUBY® – 一种四价 (2+2) 双特异性抗体形式,具有出色的功能性和 IgG 样稳定性、药理学和可开发特性

尽管现有大量双特异性抗体 (bsAb) 形式,但新型 bsAb 的产生仍然面临着开发和生物加工挑战。在这里,我们介绍 RUBY,一个不...
更新日期:2024-03-26
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