Purpose

We aimed to compare the diagnostic yield and procedure-related complications of two different types of systems for percutaneous CT-guided lung biopsy.

Material and methods

All patients with a lung lesion who underwent a CT-guided lung biopsy at our institution, between January 2019 and 2021, were retrospectively analyzed. The inclusion criteria were: (a) Procedures performed using either a fully automated tru-cut or a semi-automated full-core biopsy needle, (b) CT images demonstrating the position of the needles within the lesion, (c) histopathological result of the biopsy and (d) clinical follow-up for at least 12 months and\or surgical histopathological results. A total of 400 biopsy fulfilling the inclusion criteria were selected and enrolled in the study.

Results

Overall technical success was 100% and diagnostic accuracy was 84%. Tru-cut needles showed a significantly higher diagnostic accuracy when compared to full-core needles (91% vs. 77%, p = 0.0004) and a lower rate of pneumothorax (31% vs. 41%, p = 0.047). Due to the statistically significant different of nodules size between the two groups, we reiterated the statistical analysis splitting our population around the 20 mm cut-off for nodule size. We still observed a significant difference in diagnostic accuracy between tru-cut and full-core needles favoring the former for both smaller and larger lesions (81% vs. 71%, p = 0.025; and 92% vs. 81%; p = 0.01, respectively).

Conclusion

Our results demonstrated that the use of automated tru-cut needles is associated with higher histopathological diagnostic accuracy compared to semi-automated full-core needles for CTLB.

中文翻译：

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肺部肿瘤的组织学分析：CT 引导活检的真实切割系统与全核心系统

目的

我们的目的是比较两种不同类型的经皮 CT 引导肺活检系统的诊断率和手术相关并发症。

材料与方法

对 2019 年 1 月至 2021 年期间在我们机构接受 CT 引导肺活检的所有肺部病变患者进行回顾性分析。纳入标准为：（a）使用全自动切切或半自动全芯活检针进行的手术，（b）显示针在病变内位置的 CT 图像，（c）组织病理学结果活检和 (d) 至少 12 个月的临床随访和/或手术组织病理学结果。总共选择了 400 例符合纳入标准的活检样本并纳入该研究。

结果

总体技术成功率为 100%，诊断准确率为 84%。与全芯针相比，真切针的诊断准确性显着提高（91% vs. 77%，p  = 0.0004），并且气胸发生率较低（31% vs. 41%，p  = 0.047）。由于两组之间的结节大小存在统计学上的显着差异，我们重申了统计分析，将我们的人群以结节大小的 20 毫米截止点进行划分。我们仍然观察到，对于较小和较大病变，真切针和全芯针之间的诊断准确性存在显着差异（81% vs. 71%，p  = 0.025；92% vs. 81%；p  = 0.01 ） ， 分别）。

结论

我们的结果表明，与 CTLB 的半自动全芯针相比，使用自动切切针具有更高的组织病理学诊断准确性。