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Optimizing cultivation strategies and scaling up for fucoxanthin production using Pavlova sp.
Bioresource Technology ( IF 11.4 ) Pub Date : 2024-03-18 , DOI: 10.1016/j.biortech.2024.130609
Chun-Yen Chen , Ping-Yung Liu , Yu-Han Chang , Dillirani Nagarajan , Mary Joy D. Latagan , Mark Daniel G. de Luna , Jih-Heng Chen , Jo-Shu Chang

The microalgal-based production of fucoxanthin has emerged as an imperative research endeavor due to its antioxidant, and anticancer properties. In this study, three brown marine microalgae, namely and sp., were screened for fucoxanthin production. All strains displayed promising results, with sp. exhibiting the highest fucoxanthin content (27.91 mg/g) and productivity (1.16 mg/L·day). Moreover, the influence of various cultivation parameters, such as culture media, salinity, sodium nitrate concentration, inoculum size, light intensity, and iron concentration, were investigated and optimized, resulting in a maximum fucoxanthin productivity of 7.89 mg/L·day. The investigation was further expanded to large-scale outdoor cultivation using 50 L tubular photobioreactors, illustrating the potential of sp. and the cultivation process for future commercialization. The biomass and fucoxanthin productivity for the large-scale cultivation were 70.7 mg/L·day and 4.78 mg/L·day, respectively. Overall, the findings demonstrated considerable opportunities for fucoxanthin synthesis via microalgae cultivation and processing.

中文翻译:

使用 Pavlova s​​p. 优化种植策略并扩大岩藻黄质生产规模。

由于其抗氧化和抗癌特性,以微藻为基础的岩藻黄质生产已成为一项势在必行的研究工作。在这项研究中,筛选了三种棕色海洋微藻,即 和 sp.,用于生产岩藻黄质。所有菌株都显示出有希望的结果,其中 sp。表现出最高的岩藻黄质含量(27.91 mg/g)和生产率(1.16 mg/L·day)。此外,还研究并优化了各种培养参数(如培养基、盐度、硝酸钠浓度、接种量、光照强度和铁浓度)的影响,最终获得了最大岩藻黄质产量7.89 mg/L·day。该研究进一步扩展到使用 50 L 管式光生物反应器的大规模户外种植,说明了 sp. 的潜力。以及未来商业化的培育过程。规模化种植的生物量和岩藻黄质生产率分别为70.7 mg/L·天和4.78 mg/L·天。总体而言,研究结果表明通过微藻培养和加工合成岩藻黄质有相当多的机会。
更新日期:2024-03-18
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