Advancements in small-molecule research have created the need for sensitive techniques to accurately study biological processes in living systems. Fluorescent-labeled probes have become indispensable tools, particularly those that use boron–dipyrromethene (BODIPY) dyes. Terpenes and terpenoids are organic compounds found in nature that offer diverse biological activities, and BODIPY-based probes play a crucial role in studying these compounds. Monoterpene–BODIPY conjugates have exhibited potential for staining bacterial and fungal cells. Sesquiterpene–BODIPY derivatives have been used to study sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA), indicating their potential for drug development. Owing to their unique properties, diterpenes have been investigated using BODIPY conjugates to evaluate their mechanisms of action. Triterpene–BODIPY conjugates have been synthesized for biological studies, with different spacers affecting their cytotoxicity. Fluorescent probes, inspired by terpenoid-containing vitamins, have also been developed. Derivatives of tocopherol, coenzyme Q10, and vitamin K1 can provide insights into their oxidation–reduction abilities. All these probes have diverse applications, including the study of cell membranes to investigate immune responses and antioxidant properties. Further research in this field can help better understand and use terpenes and terpenoids in various biological contexts.

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与 BODIPY 结合的萜烯和萜类化合物：生物和化学性质概述

小分子研究的进步需要敏感技术来准确研究生命系统中的生物过程。荧光标记探针已成为不可或缺的工具，特别是那些使用硼二吡咯亚甲基 (BODIPY) 染料的探针。萜烯和萜类化合物是自然界中发现的具有多种生物活性的有机化合物，基于 BODIPY 的探针在研究这些化合物中发挥着至关重要的作用。单萜-BODIPY 缀合物表现出对细菌和真菌细胞染色的潜力。倍半萜-BODIPY衍生物已被用于研究肌浆/内质网钙ATP酶（SERCA），表明它们在药物开发方面的潜力。由于其独特的性质，人们使用 BODIPY 缀合物对二萜进行了研究，以评估其作用机制。三萜-BODIPY缀合物已被合成用于生物学研究，不同的间隔基会影响其细胞毒性。受含萜类维生素的启发，还开发了荧光探针。生育酚、辅酶 Q10 和维生素 K1 的衍生物可以深入了解它们的氧化还原能力。所有这些探针都有不同的应用，包括研究细胞膜以研究免疫反应和抗氧化特性。该领域的进一步研究可以帮助更好地理解和在各种生物环境中使用萜烯和萜类化合物。