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Electrospun PCL‐Based Materials for Health‐Care Applications: An Overview
Macromolecular Materials and Engineering ( IF 3.9 ) Pub Date : 2024-03-13 , DOI: 10.1002/mame.202300388
Teboho Clement Mokhena 1 , Mandla Brian Chabalala 2, 3 , Sivuyisiwe Mapukata 1 , Asanda Mtibe 4 , Lerato Hlekelele 4 , Zamani Cele 4 , Mokgaotsa Jonas Mochane 5 , Bulelwa Ntsendwana 1 , Toitoi Amos Nhlapo 6 , Teboho Patrick Mokoena 7 , Mokae Fanuel Bambo 1 , Kgabo Phillemon Matabola 8 , Suprakas Sinha Ray 2 , Emmanuel Rotimi Sadiku 9 , Katekani Shingange 1
Affiliation  

Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL‐based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

中文翻译:

用于医疗保健应用的电纺 PCL 基材料:概述

聚己内酯 (PCL) 是一种耐用聚合物,在众多医疗保健应用中具有潜力。其生物特性、可降解性、化学特性和机械特性可以进一步修改,以制造现代生物医学应用所需的产品。PCL 静电纺丝提供了设计类似于人体组织并促进目标部位再生的处理材料的机会。所得材料还可以通过负载其他活性功能材料进行改性以拓宽其应用。本文阐述了用于医疗保健应用的 PCL 基材料的制备和改性的最新进展。还概述了其在现代生物医学应用中的挑战和未来趋势。
更新日期:2024-03-13
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