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Merkel cell carcinoma mimicking acute leukemia
International Journal of Laboratory Hematology ( IF 3 ) Pub Date : 2024-03-13 , DOI: 10.1111/ijlh.14262
Jonathan Keow 1 , Keith F. Kwan 2 , Ben D. Hedley 2 , Cyrus C. Hsia 3 , Anargyros Xenocostas 3 , Benjamin Chin‐Yee 3
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Bone marrow aspirate showed diffuse infiltration by a population of monomorphic cells with scant cytoplasm, markedly increased nuclear-to-cytoplasmic ratio, and numerous indistinct nucleoli. Bone marrow biopsy confirmed extensive marrow infiltration by a malignant neoplasm with strong and diffuse expression of synaptophysin by immunohistochemistry, consistent with metastases from Merkel Cell carcinoma.

中文翻译:

默克尔细胞癌模仿急性白血病

骨髓抽吸物显示出一群单形细胞的弥漫性浸润,细胞质稀少,核质比显着增加,并且有许多模糊的核仁。骨髓活检通过免疫组织化学证实了恶性肿瘤的广泛骨髓浸润,突触素强且弥漫性表达,与默克尔细胞癌的转移一致。
更新日期:2024-03-13
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