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Do antibody CDR loops change conformation upon binding?
mAbs ( IF 5.3 ) Pub Date : 2024-03-13 , DOI: 10.1080/19420862.2024.2322533 Chu’nan Liu 1 , Lilian M. Denzler 1 , Oliver E.C. Hood 1 , Andrew C.R. Martin 1
mAbs ( IF 5.3 ) Pub Date : 2024-03-13 , DOI: 10.1080/19420862.2024.2322533 Chu’nan Liu 1 , Lilian M. Denzler 1 , Oliver E.C. Hood 1 , Andrew C.R. Martin 1
Affiliation
Antibodies have increasingly been developed as drugs with over 100 now licensed in the US or EU. During development, it is often necessary to increase or reduce the affinity of an antibody and rati...
中文翻译：
抗体 CDR 环在结合后会改变构象吗？
抗体越来越多地被开发为药物，目前有 100 多种抗体在美国或欧盟获得许可。在开发过程中，通常需要增加或减少抗体的亲和力和比例...
更新日期：2024-03-13
中文翻译：
抗体 CDR 环在结合后会改变构象吗？
抗体越来越多地被开发为药物，目前有 100 多种抗体在美国或欧盟获得许可。在开发过程中，通常需要增加或减少抗体的亲和力和比例...
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