当前位置：
X-MOL 学术
›
J. Diabetes Investig.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Health impacts of new‐onset diabetes in women post‐gestational diabetes mellitus: Insights from Hong Kong's territory‐wide data
Journal of Diabetes Investigation ( IF 3.2 ) Pub Date : 2024-03-08 , DOI: 10.1111/jdi.14167 Xinge Zhang 1 , Hongjiang Wu 1 , Eric SH Lau 1 , Baoqi Fan 1 , Kit Ying Tsoi 1 , Claudia HT Tam 1 , Aimin Yang 1, 2 , Mai Shi 1 , Elaine Chow 1 , Alice PS Kong 1, 2, 3 , Juliana CN Chan 1, 2, 3 , Wing Hung Tam 4 , Andrea OY Luk 1, 2, 3 , Ronald CW Ma 1, 2, 3
Journal of Diabetes Investigation ( IF 3.2 ) Pub Date : 2024-03-08 , DOI: 10.1111/jdi.14167 Xinge Zhang 1 , Hongjiang Wu 1 , Eric SH Lau 1 , Baoqi Fan 1 , Kit Ying Tsoi 1 , Claudia HT Tam 1 , Aimin Yang 1, 2 , Mai Shi 1 , Elaine Chow 1 , Alice PS Kong 1, 2, 3 , Juliana CN Chan 1, 2, 3 , Wing Hung Tam 4 , Andrea OY Luk 1, 2, 3 , Ronald CW Ma 1, 2, 3
Affiliation
|
Aims/IntroductionTo determine the population health burden attributable to the development of diabetes among women with a history of gestational diabetes mellitus (GDM).Materials and MethodsWe conducted a retrospective analysis of women with a history of GDM attending the Hong Kong Hospital Authority between 2000 and 2019. The time‐varying population attributable fraction was calculated.ResultsA total of 76,181 women with a history of gestational diabetes mellitus were included, 6,606 of them developed diabetes during a median follow‐up of 8.6 years. The respective hazard ratios (95% confidence interval) among women with GDM who developed diabetes vs those with GDM only were 2.8 (2.2, 3.7) for cardiovascular disease (CVD), 4.8 (3.0, 7.7) for end‐stage kidney disease (ESKD), 2.2 (1.9, 2.6) for infection‐related hospitalization, and 1.8 (1.3, 2.4) for all‐cause mortality. The development of diabetes was associated with 1.3 (0.8, 1.7), 0.6 (0.3, 0.8), 3.2 (2.4, 4.0), and 0.5 (0.2, 0.9) additional incident cases per 1,000 person‐years, accounting for 24.0% (13.2%, 35.9%), 42.0% (22.5%, 58.8%), 10.8% (7.1%, 14.9%), and 6.0% (−3.1%, 16.1%) of absolute number of CVD, ESKD, infection‐related hospitalization, and all‐cause mortality over 20 years after GDM, respectively.ConclusionsDiabetes is a significant contributor to the population health burden of some clinical outcomes in women with a history of gestational diabetes mellitus, but other risk factors need to be considered.
更新日期：2024-03-08
京公网安备 11010802027423号