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Maintenance oxytocin in the immediate postpartum period: Frequency, determinants and practices in a tertiary maternity unit
Journal of Gynecology Obstetrics and Human Reproduction ( IF 1.9 ) Pub Date : 2024-03-01 , DOI: 10.1016/j.jogoh.2024.102761
Inès Aubenas , Lyn Badra , Clara Rollet , François Goffinet , Camille Le Ray , Yoann Athiel

To prevent post-partum haemorrhage (PPH), national and international guidelines recommend the administration of a prophylactic injection of oxytocin after all vaginal births. Although additional maintenance oxytocin is not recommended in the immediate postpartum, its administration is quite common (30 % of French births in 2021). To assess in a single center, the frequency and determinants associated with the administration of maintenance oxytocin in immediate postpartum. A retrospective observational single-centre study was conducted in a tertiary-care university centre in Paris (France), with data from April-May 2022. All women who gave birth vaginally at or after 37 weeks, except for those with immediate PPH. Univariate and multivariate analysis were performed to compare determinants between the group receiving maintenance oxytocin and the control group without this intervention. A sensitivity analysis in a population of women at low risk of PPH was performed. Maternal, obstetrical, perinatal and organisational determinants were collected. This study included 584 patients, 278 (47.6 %) of whom received maintenance oxytocin. We observed a significantly higher rate of maintenance oxytocin administration to parous women (OR 1.57, 90 %CI 1.09–2.27) and women with a history of PPH (OR 2.88, 90 %CI 1.08–9.08). Additional maintenance oxytocin was also administered more often when the midwife handling the birth had more than 5 years of practice since completion of training (OR 1.77, 1.24–2.53) or during night-time births (OR 1.47, 90 %CI 1.03–2.10). Maintenance oxytocin administration is a frequent practice, performed for almost half the patients in our center. This practice is associated with maternal and obstetric factors, but also with health professionals' individual decisions and practices.

中文翻译:

产后立即维持催产素:三级产科病房的频率、决定因素和实践

为了预防产后出血 (PPH),国家和国际指南建议在所有阴道分娩后预防性注射催产素。尽管不建议在产后立即补充维持催产素,但其施用相当常见(2021 年法国新生儿的 30%)。旨在在单一中心评估与产后立即施用维持催产素相关的频率和决定因素。一项回顾性观察性单中心研究在巴黎(法国)的一所三级护理大学中心进行,数据来自 2022 年 4 月至 5 月。所有在 37 周或之后阴道分娩的女性(立即产后出血的女性除外)。进行单变量和多变量分析以比较接受维持催产素的组和未接受这种干预的对照组之间的决定因素。对 PPH 低风险女性群体进行了敏感性分析。收集母亲、产科、围产期和组织决定因素。这项研究包括 584 名患者,其中 278 名(47.6%)接受了维持催产素治疗。我们观察到,经产妇女(OR 1.57,90 % CI 1.09–2.27)和有 PPH 病史的妇女(OR 2.88,90 % CI 1.08–9.08)维持催产素施用率显着较高。当处理分娩的助产士自完成培训以来已经有超过 5 年的实践经验(OR 1.77,1.24–2.53)或在夜间分娩时(OR 1.47,90 % CI 1.03–2.10),也会更频繁地施用额外的维持催产素。 。维持性催产素给药是一种常见的做法,我们中心几乎一半的患者都进行了这种治疗。这种做法与孕产妇和产科因素有关,但也与卫生专业人员的个人决定和做法有关。
更新日期:2024-03-01
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