The limited lifespan of batteries is a challenge in the application of implantable electronic devices. Existing wireless power technologies such as ultrasound, near-infrared light, and magnetic field cannot charge devices implanted in deep tissues, resulting in energy attenuation through tissues and thermal generation. Herein, an ultra-low frequency magnetic energy focusing (ULFMEF) methodology was developed for the highly effective wireless powering of deep-tissue implantable devices. A portable transmitter was used to output the low-frequency magnetic field (< 50 Hz), which remotely drives the synchronous rotation of a magnetic core integrated within the pellet-like implantable device, generating an internal rotating magnetic field to induce wireless electricity on the coupled coils of the device. The ULFMEF can achieve energy transfer across thick tissue (up to 20 cm) with excellent transferred power (4–15 mW) and non-heat effects in tissues, which is remarkably superior to existing wireless powering technologies. The ULFMEF is demonstrated to wirelessly power implantable micro-LED devices for optogenetic neuromodulation and wirelessly charged an implantable battery for programmable electrical stimulation on the sciatic nerve, as well as even bypass thick and tough protective shells to power the implanted devices. The ULFMEF thus offers a highly advanced methodology for the generation of wireless powered biodevices.

中文翻译：

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超低频磁能聚焦，用于深层组织植入式电子设备的高效无线供电

电池的有限寿命是植入式电子设备应用中的一个挑战。现有的无线电力技术，如超声波、近红外光和磁场，无法为植入深层组织的设备充电，从而导致通过组织和热量产生的能量衰减。在此，开发了一种超低频磁能聚焦（ULFMEF）方法，用于深层组织植入设备的高效无线供电。使用便携式发射器输出低频磁场（<50 Hz），远程驱动集成在颗粒状植入设备内的磁芯同步旋转，产生内部旋转磁场，在设备上感应出无线电力。设备的耦合线圈。ULFMEF可以实现跨厚组织（长达20厘米）的能量传输，具有出色的传输功率（4-15 mW）并且在组织中无热效应，这明显优于现有的无线供电技术。ULFMEF 被证明可以为用于光遗传学神经调节的植入式 micro-LED 设备无线供电，并对植入式电池进行无线充电，以对坐骨神经进行可编程电刺激，甚至可以绕过厚而坚韧的保护壳为植入设备供电。因此，ULFMEF 为无线供电生物设备的生成提供了一种非常先进的方法。