Low-molecular-weight (LMW) thiols are produced in all living cells in different forms and concentrations. Glutathione (GSH), coenzyme A (CoA), bacillithiol (BSH), mycothiol (MSH), ergothioneine (ET) and trypanothione T(SH) are the main LMW thiols in eukaryotes and prokaryotes. LMW thiols serve as electron donors for thiol-dependent enzymes in redox-mediated metabolic and signaling processes, protect cellular macromolecules from oxidative and xenobiotic stress, and participate in the reduction of oxidative modifications. The level and function of LMW thiols, their oxidized disulfides and mixed disulfide conjugates in cells and tissues is tightly controlled by dedicated oxidoreductases, such as peroxiredoxins, glutaredoxins, disulfide reductases and LMW thiol transferases.

中文翻译：

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氧化还原调节和抗氧化防御中的低分子量硫醇转移酶

所有活细胞都会产生不同形式和浓度的低分子量 (LMW) 硫醇。谷胱甘肽（GSH）、辅酶A（CoA）、杆菌硫醇（BSH）、菌硫醇（MSH）、麦角硫因（ET）和锥硫酮T（SH）是真核生物和原核生物中主要的LMW硫醇。 LMW硫醇在氧化还原介导的代谢和信号传导过程中充当硫醇依赖性酶的电子供体，保护细胞大分子免受氧化和外源性应激，并参与氧化修饰的减少。细胞和组织中 LMW 硫醇、其氧化二硫化物和混合二硫键缀合物的水平和功能受到专用氧化还原酶的严格控制，例如过氧化还原酶、谷氧还蛋白、二硫键还原酶和 LMW 硫醇转移酶。