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Effects of Lung Injury and Abdominal Insufflation on Respiratory Mechanics and Lung Volume During Time-Controlled Adaptive Ventilation.
Respiratory Care ( IF 2.5 ) Pub Date : 2024-02-26 , DOI: 10.4187/respcare.11745
Harry Ramcharran , Greg Wetmore , Scott Cooper , Jacob Herrmann , Andrea F Cruz , David W Kaczka , Joshua Satalin , Sarah Blair , Penny L Andrews , Nader M Habashi , Gary F Nieman , Michaela Kollisch-Singule

Lung volume measurements are important for monitoring functional aeration and recruitment, and may help guide adjustments in ventilator settings. The expiratory phase of APRV may provide physiologic information about lung volume based on the expiratory flow-time slope, angle, and time to approach a no-flow state (TExp). We hypothesized that expiratory flow rate would correlate with estimated lung volume (ELV), as measured using a modified nitrogen washout/washin technique in a large animal lung injury model.

中文翻译:

时间控制适应性通气期间肺损伤和腹部充气对呼吸力学和肺容量的影响。

肺容量测量对于监测功能性通气和肺复张非常重要,并且可能有助于指导呼吸机设置的调整。APRV 的呼气相可以根据呼气流量-时间斜率、角度和接近无流量状态的时间 (T Exp ) 提供有关肺容量的生理信息。我们假设呼气流速与估计肺容量 (ELV) 相关,这是在大型动物肺损伤模型中使用改良的氮气冲洗/冲洗技术测量的。
更新日期:2024-02-26
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