Objective In this study we explored key prescription drug monitoring program-related outcomes among clinicians from a broad cohort of Massachusetts healthcare facilities following prescription drug monitoring program (PDMP) and electronic health record (EHR) data integration. Methods Outcomes included 7-day rolling averages of opioids prescribed, morphine milligram equivalents (MMEs) prescribed, and PDMP queries. We employed a longitudinal study design to analyze PDMP data over a 15-month study period which allowed for six and a half months of pre- and post-integration observations surrounding a two-month integration period. We used longitudinal mixed effects models to examine the effect of EHR integration on each of the key outcomes. Results Following EHR integration, PDMP queries increased both through the web-based portal and in total (0.037, [95% CI = 0.017, 0.057] and 0.056, [95% CI = 0.035, 0.077]). Both measures of clinician opioid prescribing declined throughout the study period; however no significant effect following EHR integration was observed. These results were consistent when our analysis was applied to a subset consisting only of continuous PDMP users. Conclusions Our results support EHR integration contributing to PDMP utilization by clinicians but do not support changes in opioid prescribing behavior.

中文翻译：

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电子健康记录集成后阿片类药物处方和处方药监测计划利用的变化——马萨诸塞州，2018 年

目的 在本研究中，我们根据处方药监测计划 (PDMP) 和电子健康记录 (EHR) 数据集成，探讨了来自马萨诸塞州医疗保健机构的临床医生与处方药监测计划相关的关键结果。方法 结果包括阿片类药物处方量、吗啡毫克当量 (MME) 处方量和 PDMP 查询的 7 天滚动平均值。我们采用纵向研究设计来分析 15 个月研究期内的 PDMP 数据，该研究允许围绕两个月的整合期进行六个半月的整合前和整合后观察。我们使用纵向混合效应模型来检查 EHR 整合对每个关键结果的影响。结果 EHR 集成后，通过基于 Web 的门户的 PDMP 查询数量和总数均有所增加（0.037，[95% CI = 0.017，0.057] 和 0.056，[95% CI = 0.035，0.077]）。在整个研究期间，临床医生阿片类药物处方的两项指标均有所下降；然而，EHR 整合后没有观察到显着效果。当我们的分析应用于仅由连续 PDMP 用户组成的子集时，这些结果是一致的。结论 我们的结果支持 EHR 整合有助于临床医生使用 PDMP，但不支持阿片类药物处方行为的改变。