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LC-MS/MS determination of atropine toxicity: Pre-analytical effect of blood collection tube and analytical matrix
Journal of Pharmaceutical and Biomedical Analysis ( IF 3.4 ) Pub Date : 2024-02-23 , DOI: 10.1016/j.jpba.2024.116029 Faten Farouk , Ehab Elkady
Journal of Pharmaceutical and Biomedical Analysis ( IF 3.4 ) Pub Date : 2024-02-23 , DOI: 10.1016/j.jpba.2024.116029 Faten Farouk , Ehab Elkady
Atropine (ATR) intoxication is a recurrent case in emergency departments. The diagnosis is dependent on clinical evaluation and is supported by analytical assessment The assay is limited by the rapid degradation/metabolism of ATR into TRP as well as the preanalytical factors impairing correct detection and diagnosis.
中文翻译:
LC-MS/MS 测定阿托品毒性:采血管和分析基质的分析前效果
阿托品(ATR)中毒是急诊科经常发生的病例。诊断取决于临床评估并得到分析评估的支持。该测定受到 ATR 快速降解/代谢为 TRP 以及损害正确检测和诊断的分析前因素的限制。
更新日期:2024-02-23
中文翻译:
LC-MS/MS 测定阿托品毒性:采血管和分析基质的分析前效果
阿托品(ATR)中毒是急诊科经常发生的病例。诊断取决于临床评估并得到分析评估的支持。该测定受到 ATR 快速降解/代谢为 TRP 以及损害正确检测和诊断的分析前因素的限制。