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Polydopamine interface-modulated MXene-based conductive antibacterial hydrogels for on-skin health monitoring and diabetic wound healing
Composites Part A: Applied Science and Manufacturing ( IF 8.7 ) Pub Date : 2024-02-07 , DOI: 10.1016/j.compositesa.2024.108065
Dandan Liu , Siwei Bi , Haibo Wang , Jun Gu , Shuang Wang

Flexible health management systems integrating health monitoring and wound healing capabilities are highly desirable. Electronic skins (-skins) based on conductive antibacterial hydrogels are an ideal platform for building flexible health management systems. Here, a multifunctional -skin is designed based on a conductive, antibacterial, biocompatible, self-adhesive, and stretchable hydrogel (PPMAg). The PPMAg hydrogel is developed by combining a surface-modified MXene nanocomposite (PMAg) with a P(AM-co-SBMA) matrix. The PMAg nanocomposite is designed in a heterostructured configuration by depositing Ag nanoparticles on the polydopamine interface-modulated MXene nanosheets. The PPMAg-based -skin, with a wide operating range, high sensitivity, good reproducibility, rapid responsiveness and resilience, can detect various human motions, facial expressions, and in vivo heartbeat signals. Moreover, the -skin can also promote diabetic wound healing under electrical stimulation. Thus, this study indicates that the designed -skin system has great potential to serve as a promising platform for the next generation flexible health management systems.

中文翻译:

聚多巴胺界面调制 MXene 导电抗菌水凝胶,用于皮肤健康监测和糖尿病伤口愈合

非常需要集成健康监测和伤口愈合功能的灵活的健康管理系统。基于导电抗菌水凝胶的电子皮肤(-skins)是构建灵活健康管理系统的理想平台。这里,多功能皮肤是基于导电、抗菌、生物相容、自粘和可拉伸的水凝胶(PPMAg)而设计的。PPMAg 水凝胶是通过将表面改性的 MXene 纳米复合材料 (PMAg) 与 P(AM-co-SBMA) 基质相结合而开发的。PMAg 纳米复合材料通过在聚多巴胺界面调制的 MXene 纳米片上沉积银纳米颗粒而设计为异质结构配置。基于PPMAg的皮肤具有操作范围广、灵敏度高、重现性好、反应速度快、恢复能力强等优点,可以检测各种人体动作、面部表情和体内心跳信号。此外,皮肤在电刺激下还可以促进糖尿病伤口愈合。因此,这项研究表明,所设计的皮肤系统具有作为下一代灵活健康管理系统的有前途的平台的巨大潜力。
更新日期:2024-02-07
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