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CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma
mAbs ( IF 5.3 ) Pub Date : 2024-02-13 , DOI: 10.1080/19420862.2024.2310248 Dan Zhu 1 , Haralambos Hadjivassiliou 1 , Catherine Jennings 1 , David Mikolon 1 , Massimo Ammirante 2 , Sharmistha Acharya 1 , Jon Lloyd 1 , Mahan Abbasian 1 , Rama Krishna Narla 2 , Joseph R. Piccotti 3 , Katie Stamp 3 , Ho Cho 1 , Kandasamy Hariharan 1
mAbs ( IF 5.3 ) Pub Date : 2024-02-13 , DOI: 10.1080/19420862.2024.2310248 Dan Zhu 1 , Haralambos Hadjivassiliou 1 , Catherine Jennings 1 , David Mikolon 1 , Massimo Ammirante 2 , Sharmistha Acharya 1 , Jon Lloyd 1 , Mahan Abbasian 1 , Rama Krishna Narla 2 , Joseph R. Piccotti 3 , Katie Stamp 3 , Ho Cho 1 , Kandasamy Hariharan 1
Affiliation
Cluster of differentiation 47 (CD47) is a transmembrane protein highly expressed in tumor cells that interacts with signal regulatory protein alpha (SIRPα) and triggers a “don’t eat me” signal to t...
中文翻译：
CC-96673 (BMS-986358) 是一种亲和力调节的抗 CD47 和 CD20 双特异性抗体，具有全功能 fc，选择性靶向并消除非霍奇金淋巴瘤
分化簇 47 (CD47) 是一种在肿瘤细胞中高度表达的跨膜蛋白，它与信号调节蛋白 α (SIRPα) 相互作用，并触发“别吃我”信号以...
更新日期：2024-02-16
中文翻译：
CC-96673 (BMS-986358) 是一种亲和力调节的抗 CD47 和 CD20 双特异性抗体，具有全功能 fc，选择性靶向并消除非霍奇金淋巴瘤
分化簇 47 (CD47) 是一种在肿瘤细胞中高度表达的跨膜蛋白，它与信号调节蛋白 α (SIRPα) 相互作用，并触发“别吃我”信号以...
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