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A Novel Chromone Alcohol from Portulaca oleracea
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2024-01-26 , DOI: 10.1007/s10600-024-04242-5 Hongzhe Zhang , Chengyu Wang , Chunhui Han , Fan He , Xiujuan Lan , Aijing Leng , Xixiang Ying
中文翻译:
来自马齿苋的新型色酮醇
更新日期:2024-01-26
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2024-01-26 , DOI: 10.1007/s10600-024-04242-5 Hongzhe Zhang , Chengyu Wang , Chunhui Han , Fan He , Xiujuan Lan , Aijing Leng , Xixiang Ying
A novel chromone alcohol, (S)-3,6,7-trihydroxy-2-(1-(4-hydroxyphenyl)ethyl)-4H-chromen-4-one, was isolated from Portulaca oleracea L. This compound was named oleracone P. The structure was identified by spectroscopic methods, including 1D, 2D NMR, CD, and UHPLC-ESI-Q-TOF/MS. It was found that oleracone P showed significant biological activity, inhibiting the production of inflammatory factor IL-1β at 20 μM.
中文翻译:
来自马齿苋的新型色酮醇
从马齿苋中分离得到一种新型色酮醇,(S)-3,6,7-三羟基-2-(1-(4-羟基苯基)乙基)-4H-色酮-4-酮。该化合物被命名为oleracone P。结构通过光谱方法鉴定,包括一维、二维核磁共振、CD和UHPLC-ESI-Q-TOF/MS。结果发现,oleracone P表现出显着的生物活性,在20μM时可抑制炎症因子IL- 1β的产生。