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Harmonizing the forensic nomenclature for STR loci D6S474 and DYS612
Forensic Science International: Genetics ( IF 3.1 ) Pub Date : 2024-01-21 , DOI: 10.1016/j.fsigen.2024.103012
Martin Bodner , David Ballard , Lisa A. Borsuk , Jonathan L. King , Walther Parson , Christopher Phillips , Katherine Butler Gettings

The autosomal STR D6S474 and the Y-chromosomal STR DYS612 have been reported in multiple ways in the forensic literature, with differences in both the bracketed repeat structures and counting of numerical length-based capillary electrophoresis (CE) alleles. These issues often come to light when STR loci are introduced in commercial assays and results compared with historical publications of allele frequency data, or multiple assays are characterized with reference materials. We review the forensic literature and other relevant information, and provide suggestions for the future treatment of each STR.

中文翻译:

统一 STR 基因座 D6S474 和 DYS612 的法医命名法

常染色体 STR D6S474 和 Y 染色体 STR DYS612 已在法医学文献中以多种方式进行报道,括号内的重复结构和基于数值长度的毛细管电泳 (CE) 等位基因计数存在差异。当 STR 基因座被引入商业化验并将结果与​​等位基因频率数据的历史出版物进行比较,或者用参考材料表征多个化验时,这些问题经常会暴露出来。我们回顾了法医文献和其他相关信息,并为每个 STR 的未来处理提供建议。
更新日期:2024-01-21
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