New 1,3-disubstituted 2,2-dimethylcyclopropanes of the isoxazole and pyrazole series were synthesized starting from (+)-3-carene. Olefination of the reductive ozonolysis product of (+)-4-acetyl-2-carene produced 1R-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane, further reaction of which with hydroxylamine or hydrazines led to heterocyclic compounds. It was shown that 3,5-dimethylpyrazoles could be synthesized on the surface of Al₂O₃ using ultrasonic irradiation. Studies of the antimicrobial activity of heterocyclic derivatives of dibromovinyl-2,2-dimethylcyclopropane found significant fungicidal effects of pyrazoles 8, 10, and 11 with weak antibacterial activity.

以(+)-3-蒈烯为原料，合成了异恶唑和吡唑系列的新型1,3-二取代2,2-二甲基环丙烷。 (+)-4-乙酰基-2-蒈烯的还原性臭氧解产物烯化生成1R-顺式-3-(2,2-二溴乙烯基)-2,2-二甲基环丙烷，其进一步与羟胺或肼反应得到杂环化合物。结果表明，超声波照射可以在Al ₂ O ₃表面合成3,5-二甲基吡唑。对二溴乙烯基-2,2-二甲基环丙烷杂环衍生物的抗菌活性研究发现，吡唑类8、10、11具有显着的杀菌作用，但抗菌活性较弱。