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Low-dose sugammadex reverses moderate rocuronium-induced neuromuscular block in horses
Equine Veterinary Journal ( IF 2.2 ) Pub Date : 2024-01-28 , DOI: 10.1111/evj.14066
Manuel Martin‐Flores 1 , Daniel M. Sakai 2 , Joaquin Araos 1 , Luis Campoy 1
Affiliation  

Neuromuscular block (NMB) during general anaesthesia has an implicit risk of inadvertent residual NMB during recovery. Reversal of NMB is commonly encouraged to decrease this risk, and has historically been performed with neostigmine/atropine, two agents with important cardiac and gastrointestinal side effects. Sugammadex is a new selective relaxant binding agent that can reverse rocuronium-induced NMB efficiently and without these complications. Recommended doses are possibly cost-prohibitive.

中文翻译:

低剂量舒更葡糖逆转罗库溴铵引起的马中度神经肌肉阻滞

全身麻醉期间的神经肌肉阻滞 (NMB) 存在恢复期间无意中残留 NMB 的隐含风险。通常鼓励逆转 NMB 以降低这种风险,并且历史上一直与新斯的明/阿托品一起进行,这两种药物具有严重的心脏和胃肠道副作用。Sugammadex 是一种新型选择性松弛剂结合剂,可以有效逆转罗库溴铵诱导的 NMB,且不会出现这些并发症。推荐剂量可能成本过高。
更新日期:2024-01-29
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