Objective Few studies have investigated specific associations between insomnia and orofacial pain (OFP). The aim of this cross-sectional study was to examine relationships of insomnia with pain, mental health, and physical health variables among treatment-seeking patients with chronic OFP. Methods . OFP diagnosis, demographics, insomnia symptoms, pain intensity, interference, and duration, mental health measures, and number of medical comorbidities were extracted from the medical records of 450 patients receiving an initial appointment at a university-affiliated tertiary OFP clinic. T-tests compared differences between patients with and without insomnia symptomatology, and between patients with different insomnia subtypes (delayed onset/early-wakening). Results Compared to patients without insomnia, those with elevated insomnia symptomatology (45.1%) reported higher pain intensity (60.70 ± 20.61 vs 44.15 ± 21.69; p < 0.001) and interference (43.81 ± 29.84 vs 18.40 ± 23.43; p < 0.001), depression/anxiety symptomatology (5.53 ± 3.32 vs 2.72 ± 2.66; p < 0.001), dissatisfaction with life (21.63 ± 6.95 vs 26.50 ± 6.21; p < 0.001), and number of medical comorbidities (6.72 ± 5.37 vs 4.37 ± 4.60; p < 0.001). Patients with Sleep Onset Latency insomnia (SOL-insomnia) (N = 76) reported higher pain intensity (t = 3.57; p < 0.001), and pain interference (t = 4.46; p < 0.001) compared to those without SOL-insomnia. Those with Early Morning Awakening insomnia (EMA-insomnia) (N = 71) did not significantly differ from those without EMA-insomnia on any of the variables. Differences remained significant after adjusting for age, sex, primary OFP diagnosis, and pain intensity. Conclusions Insomnia is associated with pain outcomes and should be appropriately managed when treating patients with chronic OFP.

中文翻译：

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慢性口面部疼痛患者失眠与疼痛的关系

目的 很少有研究调查失眠与口面部疼痛 (OFP) 之间的具体关联。这项横断面研究的目的是探讨寻求治疗的慢性 OFP 患者中失眠与疼痛、心理健康和身体健康变量的关系。方法 。OFP 诊断、人口统计、失眠症状、疼痛强度、干扰和持续时间、心理健康指标和医疗合并症数量是从 450 名在大学附属三级 OFP 诊所接受初次预约的患者的医疗记录中提取的。T 检验比较了有和没有失眠症状的患者之间以及不同失眠亚型（延迟发作/早醒）患者之间的差异。结果 与没有失眠的患者相比，失眠症状加重的患者（45.1%）报告了更高的疼痛强度（60.70 ± 20.61 vs 44.15 ± 21.69；p < 0.001）和干扰（43.81 ± 29.84 vs 18.40 ± 23.43；p < 0.001） 、抑郁/焦虑症状（5.53 ± 3.32 vs 2.72 ± 2.66；p < 0.001）、对生活的不满（21.63 ± 6.95 vs 26.50 ± 6.21；p < 0.001）以及医疗合并症的数量（6.72 ± 5.37 vs 4.37 ± 4.60；p＜0.001)。与没有 SOL- 的患者相比，患有入睡潜伏期失眠 (SOL-insomnia) 的患者 (N = 76) 报告了更高的疼痛强度 (t = 3.57；p < 0.001) 和疼痛干扰 (t = 4.46；p < 0.001)。失眠。患有早醒失眠 (EMA-失眠) 的患者 (N = 71) 在任何变量上与没有 EMA-失眠的患者没有显着差异。调整年龄、性别、原发性 OFP 诊断和疼痛强度后，差异仍然显着。结论 失眠与疼痛结局相关，在治疗慢性 OFP 患者时应适当管理。