Pd-catalyzed cyclization of a fluorescent dimer in which two cores of the potent estrogenic estradiol are bridged by the 1,4-diethynil benzene moiety led to a steroid dimer bearing the 1,4-di(benzofuran-2-yl)benzene. The obtained compound showed an intense blue fluorescence characterized by a broad emission band between 350 and 550 nm, with four maxima at 384, 403, 435, and 456 nm. The benzofuran dimer showed an 18-fold increased quantum yield compared with that of its synthetic precursor.

中文翻译：

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雌二醇高荧光苯并呋喃二聚体的合成与表征

钯催化荧光二聚体的环化，其中强效雌激素雌二醇的两个核心通过 1,4-二乙炔基苯部分桥接，产生带有 1,4-二（苯并呋喃-2-基）苯的类固醇二聚体。所得化合物显示出强烈的蓝色荧光，其特征在于350至550 nm之间的宽发射带，在384、403、435和456 nm处有四个最大值。与合成前体相比，苯并呋喃二聚体的量子产率提高了 18 倍。